Bafana coach Sahes Mashaba has confidence that Bafana Bafana will get through to the next round, despite a difficult draw.
Not for decades have the Soweto giants headed into the derby with such contrasting fortunes – Chiefs look unstoppable while Pirates are crumbling.
The former Bafana coach is leading a revival at Telkom Knockout finalists SuperSport United.
Inconsistent Sundowns will have to pull out all the stops to dent Amakhosi's 11-point league lead.
It was the individual power and pace of Tokelo Rantie that swung the game in South Africa's favour. He now needs to work on consistency.
The African Nations Cup will slip out of the national team's reach if they don't score big against Sudan.
Orlando Pirates take to the field for the first time since Senzo Meyiwa's death and their reaction will decide the outcome of the game.
AmaZulu's Wilfred Mugeyi, Moroka Swallows's Fani Madida and Chippa United's Roger Sikhakhane have to prove their mettle as caretaker coaches.
Quarterfinalists stumbled in midweek PSL games, but they could have held back for Telkom tournament.
Previous form against the Ivorians suggest Banyana are marginal favourites, but any optimism is tempered by the bitter memory of past letdowns.