Arsenal takes fourth place in the Premier League with a victory at Newcastle while Alex Ferguson's career ends as Man United draws 5-5 at West Brom.
Jon Walters scored two headed own goals and missed a late penalty as Chelsea won 4-0 at Stoke City to reclaim third place in the Premier League.
Liverpool were left searching for their first Premier League win under new manager Brendan Rodgers at an emotional Anfield on Sunday.
Ahead of Robin Van Persie's Manchester debut, we take stock of the tweets that made us laugh out loud following his surprise move from Arsenal.
English Premier League clubs have been warned to control their spending after a new review showed players' wages were outstripping revenue growth.
The Manchester derby has seen the pendulum swing firmly towards the blue half of the city, much to Alex Ferguson's annoyance.
Chelsea have been forced to win this season's Champions League in order to qualify for next year's after a 2-0 Premier League defeat by Newcastle.
The destiny of the Premier League title will be firmly in City's hands if they beat leaders Man United at home on Monday, Alex Ferguson has said.
Fernando Torres netted his first Chelsea hat-trick as the Champions League finalists capped a sensational by routing Queens Park Rangers 6-1.
West Ham have ensured their spot in the season final after beating Leicester 2-1 in their npower Championship away match at Walker Stadium.
Wigan Athletic have managed to keep relegation at bay after beating Arsenal 2-1 and reducing their chances of qualifying for the Champions League.
Mario Balotelli's Manchester City future was in the balance after manager Roberto Mancini admitted his patience with the striker was wearing thin.
Liverpool manager Kenny Dalglish has come under increasing pressure to get results after an embarrassing six losses in seven games.
Manchester United have moved five points clear of their city rivals after two late goals got them the win against Blackburn Rovers at Ewood Park
England striker Wayne Rooney has kept Manchester United's title bid on track after scoring the winner during the match against Fulham at Old Trafford.
Carlos Tevez has revived his side's Premier League title hopes by setting up the winning goal in Manchester City's 2-1 comeback win against Chelsea.
Steven Gerrard urged Liverpool to end the season with a flourish after hitting a spectacular Merseyside derby hat-trick on Tuesday.
The League Managers' Association chief has criticised Chelsea for sacking André Villas-Boas, saying the club was becoming an "embarrassment".
Manchester United manager Alex Ferguson says the Premier League title race will be decided by the outcome of his team's match against Manchester City.
Arsene Wenger is considering lodging a complaint with the Belgian FA, saying they "forced" Thomas Vermaelen to play even though he was injured.