Gill Marcus said she will step down from her post when her term ends in November, leaving room for one of her deputies to succeed her.
Concerns are growing that the state may be in for more bad debt than expected with African Bank.
GDP data is expected to show SA rebounded from a contraction but there still remains little momentum to spur economic growth.
Analysts have asked why regulators did not act sooner to avert the African Bank crisis.
The Reserve Bank has placed the sinking lender under curatorship in a bid to save investors.
The South African local currency is expected to continue strengthening as low volatility and high returns attract investors.
Bonds are rallying after the Reserve Bank's hiked rates in an effort to assure South Africans and investors that inflation will not run away.
Economists are split on whether the South African Reserve Bank's Monetary Policy Committee will hold or hike interest rates on Thursday.
Investors and economists will be eager to hear if the South African Reserve Bank will keep the repo rate on hold at 5.5% on Thursday.
South Africa's latest mining and manufacturing data are the highlights of an otherwise light domestic economic calendar this week.
But analysts agree that providing better guidance and more transparency can be difficult.
The Reserve Bank says the outflows from bond and equity markets since January has been double the entire amount that flowed into our shore in 2013.
The SA Reserve Bank forecasts consumer inflation in the continent's number two economy will average 6.3% in 2014. Here's your economic week ahead.
Trade and tax data have improved the outlook marginally, but consumer spending remains cautious.
Interest rates will remain unchanged, Reserve Bank governor Gill Marcus has announced, adding that the MPC's decision was split.
The former labour minister and reserve bank governor may be planning a return to politics as he steps down as AngloGold Ashanti's chairperson.
The currency has rebounded in anticipation of inflation data and higher than expected numbers could spell an end to the rand's weakness.
America's monthly jobs report and a slew of central bank meetings will dominate this week's economic calendar.
Reserve Bank governor Gill Marcus believes that while adjustments to tapering will be trying, it is ultimately good news.