The world's two richest clubs, Real Madrid and Barcelona, take up their lonely duel for the title against the league's much poorer sides.
Jose Mourinho signalled a determination to do things his way after he was unveiled as Real Madrid coach on Monday.
David Beckham was sent off in the final minute of Real Madrid's 0-0 home draw with lowly Real Betis in the Primera Liga on Saturday. The former England captain, making his 150th appearance for the club, was shown a straight red card for a late challenge on Isidoro.
A magnificent Ronaldinho led Barcelona to a dramatic 3-1 comeback win over Real Zaragoza in the Nou Camp on Sunday which moved them back to the top of the Primera Liga. After the European and Spanish champions had fallen behind to an early strike from Zaragoza's Gabriel Milito, the Brazilian playmaker headed Barca level in the 30th minute.