Nigeria dismissed Stephen Keshi despite his side's home win against Sudan that kept them in the running to defend their African Cup of Nations title.
Ghana is set to battle Tunisia in its quest to end a 30-year wait for an Africa Cup of Nations title and secure a place in the semi-finals.
The Africa Cup of Nations group D will serve up a second West African derby when Ghana face Mali on Saturday.
Officials, players and fans reacted on Monday with disbelief and anger following the country's suspension by Fifa.
Defending champions Egypt defeated Nigeria 3-1 in their opening Africa Cup of Nations Group C match at the Ombaka Stadium here on Tuesday.
The sleepy town of Benguala will come alive on Tuesday when defending champions Egypt and Nigeria clash in the Africa Cup of Nations Group C match.
Defending champions Egypt continued their African Nations Cup title defence by beating neighbours Sudan 3-0 in Group C on Saturday. Egypt top the group with six points from two matches while Cameroon moved into second spot after their 5-1 hammering of Zambia.
Ghana aim to give their long-suffering fans something to smile about when they make their World Cup debut after a 44-year wait to play in the finals. One of Africa's most powerful footballing nations, the "Black Stars" have won the Nations Cup four times while their clubs and teams have dominated continental and junior international competitions.