/ 27 March 2002

Doctors crack mystery Pacific disease

EATING flying foxes which had consumed palm seeds may be the

reason why a small group of Pacific Island people were devastated

by a terrifying mental illness, according to new research published in an American academic journal, Neurology.

It reports that the disease may have declined because fruit bats on Guam

died out and the imported Samoan flying foxes do not eat palm

seeds.
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One of those who solved the mystery is the celebrated New York

neurologist Oliver Sacks whose best known book, ”Awakenings”, was

turned into a movie in which he was played by Robin Williams. It

told of how he used the drug L-Dopa to bring post-encephalitic

patients out of deep comas.

The indigenous Chamorro people of Guam have at times been devastated

by lytico-bodig, an extremely rare mental disease which leaves

people seemingly conscious and awake, but completely vacant.

There is no cure. It has also been recorded in a part of Japan

and Papua New Guinea and today is known as ”amyotrophic lateral

sclerosis/parkinsonism-dementia” (ALS-PDS).

Sacks and Dr Paul Cox of Hawaii’s National Tropical Botanical

Garden write in Neurology that the high incidence of ALS-PDC had

been an enigma.

Confined to the Chamorro it climaxed in the 1940s when it was

the main cause of adult death and today it only occurs in older

adults and rarely in any individual born after 1960.

There was no genetic link to the disease, nor infectious origin.

Researchers suspected the seeds of the cycad palm tree but

Chamorro knew they were toxic and only ate the seeds in a flour

form which washed out the toxins.

”We suggest that the Chamorro … ingested large quantities of

cycad toxins indirectly by eating flying foxes,” Sacks and Cox

write.

They were eaten in ceremonial occasions and their consumption

was a core part of Chamorro custom, particularly in the villages of

Umatac and Inarajan – both of which have the highest incidences of

the disease.

The authors found the flying foxes sometimes consume up to two-and-a-half times their body weight per night in fruit and nectar –

and that they were particularly fond of cycad seeds.

Eating the bats became highly popular and by the late 1970s the

species had been hunted to near extinction.

Sacks and Cox say massive importation of flying foxes from Samoa

followed: about 18 000 flying foxes at $35 a carcass.

The Pacific Daily News in Guam reported on Wednesday that the Chamorro were still occasionally eating local flying foxes.

”People should not be unduly frightened if they have eaten fruit

bat,” University of Guam expert Ulla-Katrina Craig told the

newspaper.- Sapa-AFP