President Cyril Ramaphosa will announce changes to the Cabinet at 8.30pm on Monday at the Union Buildings in Pretoria, the Presidency has confirmed.
Ramaphosa is also expected to announce a new deputy president.
The Cabinet reshuffle comes amid growing calls to fire ministers implicated in state capture.
The ministers seen as being compromised or underperforming are Social Development Minister Bathabile Dlamini, Water Affairs Minister Nomvula Mokonyane, Co-operative Governance Minister Des van Rooyen, Mineral Resources Minister Mosebenzi Zwane, Public Service Minister Faith Muthambi and Finance Minister Malusi Gigaba, a source close to Ramaphosa has told the Mail & Guardian.
Speaking to News24, ANC national spokesperson Pule Mabe confirmed that former finance minister Nhlanhla Nene will be sworn in as a member of parliament rousing speculation that Nene may return to his previous position.
This article has been updated.