/ 4 October 2010

Test-tube baby pioneer wins Nobel prize

British physiologist Robert Edwards, whose work led to the first “test-tube baby”, won the 2010 Nobel prize for medicine, Sweden’s Karolinska Institute said on Monday.

The Institute lauded Edwards (85) for bringing joy to infertile people all over the world.

Known as the father of in-vitro fertilisation (IVF), Edwards picked up the prize of $1,5-million for a “milestone in the development of modern medicine”, the institute said.

As many as four-million babies have been born since the first test-tube baby in 1978, using the techniques Edwards developed, together with a now-deceased colleague, Patrick Steptoe, it said.

They soldiered on despite opposition from churches, governments and many in the media, as well as scepticism from scientific colleagues.

“His achievements have made it possible to treat infertility, a medical condition afflicting a large proportion of humanity including more than 10% of all couples worldwide,” the institute said.

In 1968, Edwards and Steptoe, a gynaecologist, developed methods to fertilise human eggs outside the body.

Working at Cambridge University, they began replacing embryos in infertile mothers in 1972. But several pregnancies spontaneously aborted due to what they later discovered were flawed hormone treatments.

In 1977, they tried a new procedure which did not involve hormone treatments and relied instead on precise timing. On July 25 of the next year, Louise Brown, the first test-tube baby, was born.

Edwards and Steptoe founded the first IVF clinic at Cambridge in 1980. Soon after, thousands of test-tube babies were being born in Britain, the United States and elsewhere.

“The most important thing in life is having a child,” Edwards has been quoted by his clinic as saying: “Nothing is more special than a child.”

Steptoe died in 1988.

Edwards, whose publicist said he is now too ill to give interviews, has mostly been out of the limelight. He won the Lasker Clinical Medical Reserach Award in 2001.

Reactions to the prize
Medicine is traditionally the first of the Nobel prizes awarded each year. Prizes for achievements in science, literature and peace were first awarded in 1901 accordance with the will of dynamite inventor and businessman Alfred Nobel.

Here are some reactions to the announcement of the award:

Louise Brown, who was the world’s first test tube baby born in July 1978: “Its fantastic news. Me and mum are so glad that one of the pioneers of IVF has been given the recognition he deserves. We hold Bob in great affection and are delighted to send our personal congratulations to him and his family at this time.”

Dr Alan Thornhill, scientific director of London Bridge Fertility, Gynaecology and Genetics Centre: “Bob Edwards changed the way we think about having babies. The IVF technique pioneered by Professor Edwards has and will continue to accelerate developments in many other areas of medicine.”

Robert Edward’s wife, Ruth, and his family: “We are thrilled and delighted that Professor Edwards has been awarded the Nobel Prize for the development of IVF. The success of this research has touched the lives of millions of people worldwide.” – Sapa.-AFP