Noah is showcasing his new show "Born a Crime" in New York until June 8. He performed a five-minute routine which was well-received by the live audience in New York.
He tweeted after the show: "To the amazing audience that carried me through tonight's show, I cannot thank you enough. You were power."
Noah's performance on the Leno show early last year was hailed abroad and at home in South Africa. It was the first time an African comedian had taken the mic on stand-up comedy's biggest traditional showcase.
The South African media heaped praise on Noah for his appearance and MSNBC Africa rebroadcast the show across the continent.
Last year Noah spent a few months in Southern California. "I've always wanted to be a comedian in the world," Noah said at the time. "I don't want to be labeled a South African comedian."
Noah (29) spearheads a generation of South African stand-ups who have become wildly popular, providing not only escapism but also a different perspective on the nation's problems. They tackle race, class, crime, corruption and the political elite. As court jesters tweaking the nose of the powerful, they are quite possibly helping to keep the nation sane.
Noah's show, That's Racist, runs the gamut from road tolls and shark attacks to the Marikana mine massacre and the bedroom antics of President Zuma.