"We have about 2 948 public health facilities now initiating patients on anti-retroviral treatment compared to 495 in January 2010," he said in a statement.
"One of our greatest success stories is the remarkable 50% reduction in mother-to-child transmission of HIV from about 8% in 2008 to 3.5% in 2011."
The country now had more than 1.7-million South Africans on anti-retroviral treatment, which had improved life expectancy dramatically, he said.
Zuma's remarks were made after United Nations Aids executive director Michel Sidibé visited him at his Mahlamba Ndlopfu residence in Pretoria.
Sidibé congratulated Zuma and South Africa on the strides the country was making in the global fight against HIV and Aids. He asked that South Africa lead efforts in Africa, especially in manufacturing their own medicine and thus reducing dependency on countries outside the continent.
Zuma added how remarkable it was that more than 20-million people had been tested for HIV through the counselling and testing campaign he launched publicly in 2010.
"This indicates that the stigma around the disease is being eradicated, which will assist our continued prevention efforts; and the rate of new HIV infections looks set to decline over the coming years, as we deepen our existing programmes." – Sapa